Occasionally when switching from full screen to windowed, and once just playing the game windowed, Minecraft will lock the entire MacBook Pro.
The machine will be briefly responsive for around 2 seconds every few minutes, other than that it's frozen. The system log has repeated entries for:
kernel: NVDA(OpenGL): Channel timeout!
Usually a forced power off is the only solution.
This has only started happening in the last month or two. This machine is used heavily, Minecraft is the only app causing this.