In my world I have areas that have a market that uses villagers, and another shop maybe a couple hundred blocks away that uses End Crystals as decoration, as well as a "Host Area" that's constantly loaded with a ticking area.

I loaded my world up last night and all the villagers at the market were gone, armour stands at the market and the end crystals a couple hundred blocks away were all at the Host Area which is thousands of blocks away, there was an explosion sized hole in a wall, all the armour stands were under the water at the host area, as well as a random villager from the market but none of the others, as well as another end crystal floating outside the wall, all things which have moved THOUSANDS of blocks away from where they were placed, but conveniently this all takes place at my ticking area, so there's a possible connection there.