I understand that using the Material Reducer with any block could make no sense. For example, ¿what can you expect if you reduce a redstone repeater, a bucket of tropical fish or a jigsaw? But, some other blocks that do make sense or could make sense (taking into account the blocks are used) aren't working.

Steps to Reproduce:

1. Open a creative world with the education edition features enabled.
2. Put a Material Reducer on the ground.
3. Pick up any of these elements:

• Stone stair
• Stone slab
• Polished stone
• Polished stone slab
• Copper ore
• Deepslate
• Tuff
• Any deepslate ore variant
• Nether gold ore
• Basalt
• Podzol
• Coarse dirt
• Powder snow
• Blackstone
• Soul soil
• Nylium
• Moss block
• Calcite
• Amethyst
• Rooted dirt
• Any nether stem, hyphae or planks

     4.  Try to place it into the Material Reducer's input.

Observed Results:
That blocks aren't moved to the input.

Expected Results:
Each block should be reduced accordingly with the following list:

• Stone stair, stone slab, polished stone, polished stone slab, deepslate, tuff, basalt or blacksone: Si67 O33
• Copper ore: Cu64 Si12 O24
• Any deepslate ore variant: (The same as their corresponding stone variant)
• Nether gold ore: Au64 Si23 O7 Hg5 ???
• Podzol or coarse dirt: Si21 Ca8 P3 N3 Fe13 Mg6 Zn2 Cu2 O42
• Powder snow: H67 O33
• Soul soil: Si63 O12 ???25
• Nylium or moss block: C15 O70 N8 P7
• Calcite: Ca20 C20 O60
• Amethyst: Si25 O50 Fe25
• Any nether stem, hyphae or planks: C49 H6 O44 N

You must take into account that this is only an approach  made by a non-expert and all recipes can be changed for making it more accurate.

As Ancient Debris is also an ore, I think it could be included, but I have no idea how can be it's composition.