Creepers you use the love medallion on while they are running at you will still explode, this could be a annoying way to fail a tower run, saying that from experience.

Steps to reproduce

1) Get a Love Medallion equipped
2) Get a creeper to charge at you
3) Charm the creeper(s) with the artifact
4) watch as they blow you up anyways. (i've only tested experienced it in the tower)