I have played our world with my two kids. We have had multiple items despawn. Enchanted fishing rods, anvils, blast furnaces, ore, and saved animals. This has happened both inside chests and in player inventory. 

This world has always been loaded on my sons xbox one s (50+ hours.) This morning I loaded it on my xbox one x (through his profile.) The game said it had to sync then loaded. 

To our horror, the last around 6 hours of gameplay had been lost. Then when we tried to use our nether portal hub to "jump" to a different area, our nether hub had totally been destroyed.  We had set ups in three different locations in what would have been an entire world away from each "jump."

In conclusion, this means when the game was loaded from the same profile on a different xbox, our save was corrupted and an entire world with close to 100 hours of combined gameplay was lost.