I've noticed that some items, although I haven't tested EVERY item with a cooldown, seem to make the player move slower, and doesn't disengage the animation whilst the use key is being held. This is further expressed in the video titled "Goat Horn Chaos".¹ Ender pearls, however, most likely due to the fact that they decrease the item in the stack when used before starting the cooldown, are NOT affected, as shown in the video titled "Ender Pearl Success".

¹Please note I had to re-record Goat Horn Chaos Multiple times because it was too long to fit in initially.