Though a 1 redstone-tick pulse don't activate comparators from its main input, it will deactivate it when comparing or subtracting redstone signals, as long as a comparator is facing into the side of a repeater locking it. Otherwise, the comparator will not be deactivated. Either this shouldn't happen since comparators aren't normally affected by 1 redstone-tick pulses, or comparators not being affected normally by 1 redstone-tick pulses is a bug.

How to reproduce:

1. Place a comparator.
2. Put a container behind the comparator with one item in it.
3. Have redstone dust next to the comparator.
4. Have an observer block facing into the redstone dust.
5. Put a repeater sideways in front of the comparator, locking it.
   When you activate the observer, the repeater will unlock, then relock.