Normally nether stars cannot be destroyed with explosions, however, blowing up a bundle/shulker box that contains a nether star can destroy it.
Nether stars are blown up when in an item frame
It is possible to destroy netherite items with lava by putting them inside a container
Netherite can burn whilst inside of a bundle
Nether stars in suspicious sand and suspicious gravel are not explosion-proof
Curse of vanishing items dont despawn inside shulker boxes or bundles.
Items do not hold their properties inside of item frames