Minecraft 1.12 worked fine, but in Minecraft 1.13 as soon as I enter full screen mode, left mouse click buttons seem no longer reliably get recognized by the game, it takes up to 2-3 clicks in the the main menu for a button to register the mouse click.

Minecraft 1.13.1 worsened the problem, there it won't even properly register mouse clicks in windowed mode.

As mentioned the issue does not exist in 1.12. When I launch 1.12 the mouse works fine in both windowed and full screen mode. 

This makes 1.13.1 pretty much unplayable. Please do let me know if i can provide any more information.