In creative mode, right clicking with a single empty map will replace it in your hotbar with a map, while right-clicking with multiple empty maps (2-64) will not use up any empty maps and will create a map in a different location in your inventory.
Empty map is consumed in creative mode
Using fire charges on TNT in creative mode consumes the fire charge
Can't fill an empty map in creative mode
Using empty map in creative mode can create additional map with ID 0
Glass Bottle is consumed upon right-click on a water source/cauldron in creative